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TEM pictures of assembly products: (A) Empty NΔ34 capsids showing significant size variability. (B) NΔ34 VLPs from an unpurified assembly reaction showing incorporation of gold cores although at a lower efficiency. Inset: higher magnification micrograph for a more detailed view of the complexes. (C) VLPs from an unpurified assembly reaction with wild-type CCMV capsid. (D) NΔ34 VLPs purified over a sucrose density gradient.
