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. Author manuscript; available in PMC: 2009 Sep 28.
Published in final edited form as: Cell. 1990 Aug 10;62(3):469–480. doi: 10.1016/0092-8674(90)90012-4

Figure 3. stg Expression in G2 of Cycle 14 Induces Mitosis.

Figure 3

(A), (B), and (C) show ventral views of hs-stg embryos that were fixed and stained with anti-cyclin A antibodies 0, 5, and 15 min after a 25 min heat pulse (37°C), initiated at 175 min AED. Cyclin degradation, which occurs at metaphase, occurs in a stochastic pattern that encompasses virtually all of the embryonic cells within 15 min of the heat pulse. See Figures 2A, 2B, and 2C for normal cyclin A expression patterns during cycle 14. (D) shows anaphase chromosomes in a hs-stg–induced mitosis. Note the absence of abnormalities such as chromosome bridges.