. Author manuscript; available in PMC: 2010 Jul 9.

Published in final edited form as: J Med Chem. 2009 Jul 9;52(13):3892–3901. doi: 10.1021/jm9002704

Table 2.

Summary of β-Aminoarylketones with Alternate Aromatic Rings


Compound Number	Aryl Ring	SRC Binding Inhibition, TRβ (IC₅₀, µM)^a	Cell viability HepG 2 (EC₅₀, µM) ^b
9		16.5±1.4	65±19
13{1}		4.0±0.4	38±6
13{2}		>50	>130
13{3}		>50	>65±14

Values are the mean of three independent experiments in triplicate.

Values are means of two independent experiments in triplicate. The general error limits are ±5%.