Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of α-Substituted β-Aminophenylketones
 | |||
|---|---|---|---|
| Compound Number | R | SRC Binding Inhibition, TRβ (IC50, µM)a | Cell viability HepG 2 (EC50, µM)b |
| 9 | H | 16.5±1.5 | 65±19 |
| 14{1} | Me | >50 | 56±18 |
| 14{2} | iPr | >50 | 62±27 |
| 14{3} | Ph | >50 | 27±19 |
| 14{4} |  |
1.7±0.3 | 14±2 |
| 14{5} |  |
2.3±0.2 | 12±2 |
| 14{6} |  |
1.6±0.1 | 12±1 |
Values are the mean of three independent experiments in triplicate.
Values are means of two independent experiments in triplicate. The general error limits are ±5%.
