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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: J Addict Med. 2009 Jun 1;3(2):47–54. doi: 10.1097/ADM.0b013e31819ca788

Table 1.

Overview of neural response patterns during normal adolescent development

Response in Typical Development
IFC Striatum
Adolescents 30–32, 50, 60–61 ⬇ ⬆
At-risk Adolescents 39 ⬇⬇ ?

⬇ = less neural response; ⬆ = greater neural response;? = no known results

Overview of neural response patterns during normal adolescent development. Relative to adults, typical adolescents show less in inferior frontal cortex (IFC) response during inhibitory control tasks, but a greater striatal response during reward processing. Relative to typical adolescents, adolescents at-risk for substance abuse show less response in the IFC during inhibitory control.