Table 1.
Characteristics of 10,266 KP Chronic Kidney Disease Enrollees and Univariate Associations With Type 2 Diabetes Status
| Baseline Characteristics | Total Cohort N = 10266 (100) (% or SD) | Diabetic CKD N = 2508 (24.43)(% or SD) | Non diabetic CKD N = 7758 (75.56) (% or SD) | Odds Ratio (diabetic CKD vs non diabetic CKD) | P value |
|---|---|---|---|---|---|
| Mean age (continuous) | 63.06 (13.43) | 63.50 (11.63) | 62.92 (13.96) | NA | 0.0386 |
| Mean eGFR* (continuous) | 48.81 (10.11) | 46.04 (11.46) | 49.57 (9.52) | NA | < .0001 |
| Men | 4155 (40.47) | 1111 (26.74) | 3044 (73.26) | 1.23 (1.12-1.34) | < .0001 |
| Hypertension | 7916 (77.11) | 2297 (29.02) | 5619 (70.98) | 4.14 (3.56-4.81) | < .0001 |
| eGFR 50-59 | 5868 (57.16) | 1220 (20.79) | 4648 (79.21) | 1.00 (Referent) | - |
| eGFR 40-49 | 2593 (25.26) | 657 (25.34) | 1936 (74.66) | 1.29 (1.16-1.44) | - |
| eGFR 30-49 | 1142 (11.12) | 367 (32.14) | 775 (67.86) | 1.80 (1.57- 2.07) | - |
| eGFR 20-39 | 457 (4.45) | 171 (37.42) | 286 (62.58) | 2.27 (1.86- 2.78) | - |
| eGFR 10-19 | 206 (2.01) | 93 (45.15) | 113 (54.85) | 3.13 (2.36- 4.15) | < 0.0001** |
| Coronary artery disease | 1335 (13.00) | 451 (33.78) | 884 (66.22) | 1.70 (1.50-1.92) | < .0001 |
| Chronic heart failure | 750 (7.31) | 293 (39.07) | 457(60.93) | 2.11 (1.81-2.46) | < .0001 |
| Cerebrovascular disease | 163 (1.59) | 62 (38.04) | 101 (61.96) | 1.92 (1.39-2.64) | < .0001 |
| Peripheral artery disease | 490 (4.77) | 253 (51.63) | 237 (48.37) | 3.56 (2.96-4.27) | < .0001 |
| ACEI use | 1500 14.61) | 631 (42.07) | 869 (57.93) | 2.66 (2.37-2.98) | < .0001 |
| ARB use | 156 (1.52) | 71 (45.51) | 85 (54.49) | 2.63 (1.91-3.61) | < .0001 |
| Statin use | 1448 (14.10) | 476 (32.87) | 972 (67.13) | 1.63 (1.45-1.84) | < .0001 |
| NSAID use | 1213 (11.82) | 228 (18.80) | 985 (81.20) | 0.68 (0.59-0.80) | < .0001 |
*eGFR in ml/min/1.73 m2; ** P value for trend