Table 4.
BPI scores at baseline and end point (overall and by previous treatment)
| Treatment in previous study | |||
|
BPI variable Mean (SD) |
OROS® hydromorphone (n = 35) |
CR morphine (n = 33) |
Overall (n = 68) |
| Pain at its worst1 | |||
| Baseline | 4.3 (2.30) | 5.1 (2.78) | 4.7 (2.57) |
| End point | 5.9 (2.58) | 5.8 (2.98) | 5.9 (2.76) |
| Pain at its least1 | |||
| Baseline | 1.3 (1.23) | 1.8 (1.91) | 1.6 (1.62) |
| End point | 2.2 (1.81) | 2.4 (2.43) | 2.3 (2.12) |
| Pain on average1 | |||
| Baseline | 2.8 (1.89) | 3.2 (2.10) | 3.0 (2.00) |
| End point | 3.9 (2.30) | 3.8 (2.50) | 3.9 (2.38) |
| Current pain1 | |||
| Baseline | 1.8 (1.84) | 2.5 (2.21) | 2.2 (2.05) |
| End point | 3.3 (2.86) | 3.5 (2.49) | 3.4 (2.67) |
| Pain relief2 | |||
| Baseline | 74.4 (22.13) | 70.0 (23.56) | 72.2 (22.78) |
| End point | 61.5 (27.40) | 58.2 (28.11) | 59.8 (27.60) |
Baseline = absolute values; end point = last observation carried forward
10 = no pain, 10 = pain as bad as you can imagine; 20% to 100%
BPI, brief pain inventory; CR, controlled-release; SD, standard deviation