Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Scheme for biomarker discovery, qualification, verification and validation. Solid phase enrichment of N‐glycopeptides (SPEG) can be performed to discover in vivo disease‐specific signatures using cells, tissue and finally blood plasma and MS‐based label‐free quantification. The selected reaction monitoring (SRM) assays of these protein panel are then qualified and later verified in human patients by SRM and eventually validated again by SRM or ELISA.
