Table 2.
List of markers in clinical use including their status of glycosylation.
| Protein Names | Plasma concentration in controls pg/ml | Clinical Markers | SwissProt # (human) | Glycosylation | FDA approved |
|---|---|---|---|---|---|
| Alkaline phosphatase, placental type | √ | P05187 | yes | ||
| Alpha‐fetoprotein | 2.00E+04 | √ | P02771 | yes | √ |
| CA 125 | √ | Q8WXI7 | yes | √ | |
| CA 15.3 | √ | P15941 | yes | √ | |
| CA 19.9 | √ | x | yes | √ | |
| CA 27.29 | √ | x | yes | ||
| CA 72‐4 | √ | x | yes | ||
| Carcinoembryonic antigen | 1.00E+03 | √ | P06731 | yes | √ |
| Choriogonadotropin beta chain | 1.00E+02 | √ | P01233 | yes | |
| Chromogranin A (parathyroid secretory protein 1) | 6.50E+04 | √ | P10645 | yes | |
| Colony stimulating factor 1 (macrophage) | 7.00E+01 | √ | P09603 | yes | |
| Complement factor H related protein | √ | Q03591 | yes | √ | |
| Corticotropin‐lipotropin contains ACTH | 1.10E+01 | √ | P01189 | yes | |
| Epidermal growth factor receptor | 6.94E+06 | √ | P00533 | yes | |
| Follicle‐stimulating hormone | √ | P01225 | yes | ||
| Hepatocyte growth factor | 2.00E+02 | √ | P14210 | yes | |
| Inhibin | 3.00E+03 | √ | P05111 | yes | |
| Kallikrein 10 | 4.39E+02 | √ | O43240 | yes | |
| Kallikrein 11 | 2.15E+06 | √ | Q9UBX7 | yes | |
| Kallikrein 3 (prostate specific antigen) | 1.86E+03 | √ | P07288 | yes | √ |
| Kallikrein 5 | √ | Q9Y337 | yes | ||
| Kallikrein 6 | 2.90E+03 | √ | Q92876 | yes | |
| Kallikrein 7 | √ | P49862 | yes | ||
| Kallikrein 8 | √ | O60259 | yes | ||
| Luteinizing hormone‐releasing hormone receptor | √ | P22888 | yes | ||
| Mesothelin | √ | Q13421 | yes | ||
| MK‐1 protein, Ep‐CAM | 2.00E+03 | √ | P16422 | yes | |
| OVX1 | √ | x | yes | ||
| Prolactin | 1.60E+04 | √ | P01236 | yes | √ |
| soluble IL‐2R alpha | 1.42E+03 | √ | P01589 | yes | |
| Somatotropin growth factor, growth hormone | 4.00E+02 | √ | P01241 | yes | |
| Thyroglobulin | 1.00E+03 | √ | P01266 | yes | √ |
| V‐erb‐b2, Her2/neu | 1.12E+04 | √ | P04626 | yes | √ |
| Vascular endothelial growth factor A, VEGF | 2.01E+02 | √ | P15692 | yes | |
| Calcitonin | 1.00E+01 | √ | P01258 | no | |
| Estrogen receptor 1 | √ | P03372 | no | ||
| Gastrin | 6.90E+02 | √ | P01350 | no | |
| Insulin | √ | P01308 | no | ||
| Parathyroid hormone‐related protein | √ | P12272 | no | ||
| Progesterone receptor | √ | P06401 | no | ||
| Somatostatin | 2.00E+01 | √ | P61278 | no | |
| Vasoactive intestinal peptide | √ | P01282 | no |