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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Jul 16;29(10):1458–1464. doi: 10.1161/ATVBAHA.109.192658

Figure 3. MCP-1 release (A) and macrophage migration (B) in periaortic adipose tissue explants from abdominal aortas are increased by obesity.

Figure 3

Periaortic adipose tissue explants were prepared from thoracic or abdominal aortas of LF- and HF-fed mice (4 months) and incubated as described. A, MCP-1 release into the media was increased in periaortic explants of abdominal aortas from HF compared to LF-fed mice. There was no effect of HF-feeding on MCP-1 release from thoracic periaortic adipose tissue explants. B, Mouse peritoneal macrophage migration was increased by conditioned media from abdominal periaortic adipose explants of HF compared to LF-fed mice.*, significantly different from LF abdominal. Inline graphic, significantly different from HF-thoracic. Data are mean ± SEM from n = 5 mice/group.