Table 5.
Features associated with any serious conditions (cryptococcal meningitis, cerebral toxoplasmosis or tuberculous meningitis)
| Cryptococcal meningitis | Serious condition | |||
|---|---|---|---|---|
| Odds ratio (95% CI) |
p-value | Odds ratio (95% CI) |
p-value | |
| Sex (male) | 3.4 (1.4, 9.0) | 0.011 | 4.0 (1.6, 10.3) | 0.003 |
| CD4 | ||||
| <50 | 47.3 (8.6, 901) | < 0.001 | 9.4 (2.6, 46.4) | 0.002 |
| 50-199 | 23.5 (4.1, 454) | 0.004 | 7.5 (2.0, 37.4) | 0.006 |
| ≥200 | 1 (Ref.) | 1 (Ref.) | ||
| Change in position worsens headache | 21.4 (3.9, 407) | 0.005 | 6.3 (1.9, 26.0) | 0.005 |
| Neck stiffness | 9.2 (1.8, 82.8) | 0.019 | 32.2 (4.2, 719) | 0.004 |
| WHO stage | ||||
| I & II | 1 (Ref.) | |||
| III | ? | ? | 4.2 (1.0, 24.4) | 0.066 |
| IV | ? | ? | 6.5 (1.6, 37.6) | 0.016 |
Note: Odds ratios, confidence intervals (95% CI) and p-values calculated from multivariate logistic regression model. All variables included in the final multivariate model are shown. Variables considered in the step-wise procedure were: gender, headache location (Cryptococcal meningitis only), WHO stage, CD4 cell count, change in head position worsens headache, neck stiffness, Kernig's sign and papilloedema.