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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Pharmacol Biochem Behav. 2009 Aug 22;94(1):204–210. doi: 10.1016/j.pbb.2009.08.011

Figure 4.

Figure 4

Cocaine self-administration was reliable during the maintenance phase, and extinguished readily in 2 sessions in four squirrel monkeys. Subsequently, non-contingent injections of cocaine (0.3 and 1.0 mg/kg) reinstated responding. LY379268 pretreatment demonstrated a strong trend toward significantly attenuating reinstatement of responding induced by the high dose (1.0 mg/kg) of cocaine. Abscissa: day of treatment and pretreatment dose of LY379268 prior to reinstatement tests. Ordinate: rates of responding expressed as a percent of baseline control rates.