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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Methods. 2009 May 4;49(2):101–111. doi: 10.1016/j.ymeth.2009.04.016

Fig. 5.

Fig. 5

Raman difference spectra of (a) [CMP pH 6.0] minus [CMP pH 3.0] and (b) [HDV pH 7.5] minus [HDV pH 5.0]. The HDV ribozyme crystal was surrounded by cacodylate buffer (pH7.5) or acetate buffer (pH5.0) containing 20 mM Mg2+. Peak assignments are provided in Table 4. Adapted with permission from [26]. (Copyright, American Chemical Society.)