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. 2009 Oct 8;4(10):e7350. doi: 10.1371/journal.pone.0007350

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Autiero et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The surface of Sirt-1 binding groove of the selected complexes between AROS and Sirt-1, obtained using CLUSPRO (CL10 and CL2), PATCHDOCK (PD7 and PD12) and GRAMMX (GX6 AND GX2) servers. The colours correspond to the chemical properties of each residue. The acid residue are coloured in red, the basic residue are coloured in blue, the hydrophobic residues are coloured in orange and the hydrophilic residues are coloured in green. The oval lines indicate the basic top and the acid bottom, respectively.