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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: J Cell Physiol. 2009 Jun;219(3):659–666. doi: 10.1002/jcp.21712

FIGURE 4. Msx2 expression causes NMuMG invasive ability in a c-Src kinase activity dependent manner.

FIGURE 4

(a) Photomicrographs of 3D Matrigel cultures of NMuMG-EV and NMuMG-Msx2 cells treated with DMSO as control and with c-Src inhibitor SU6656 (10μM) or with Alk4/5/7 inhibitor SB-431542 (10μM). (b) Western blot analysis using the phospho-specific antibody p-Src (Y416) on total cell lysates extracted from NMuMG-EV (EV) and NMuMG-Msx2 (Msx2) cells treated for 6h with c-Src inhibitor SU6656 (10μM) or with DMSO as control. (c) Photomicrographs of cells that invaded through the Matrigel invasion chamber. The cells were fixed and stained with crystal violet. Magnification at 4×. (d) Histogram represents the number of cells that invaded through the Matrigel invasion chamber, counted after fixation and crystal violet staining.

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