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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Psychopharmacology (Berl). 2009 Jun 10;206(1):73–84. doi: 10.1007/s00213-009-1581-9

Table 1.

ED50 values (doses estimated to engender 50% drug-lever responses) for cocaine, PD 128907 and sumanirole following pretreatment with vehicle or 17.8 mg/kg of CJB 090. Values are means (± SEM) determined from individual dose-response functions of squirrel monkeys (n=5 or 6).

Agonist ED50 (mg/kg)
Vehicle CJB 090 (17.8 mg/kg)
Cocaine 0.11 ± 0.01 0.40 ± 0.06*
PD 128907 0.17 ± 0.02 0.55 ± 0.14*
Sumanirole 2.26 ± 0.24 1.63 ± 0.17†
*

significant increase compared to vehicle pretreatment (p<0.05).

†

significant decrease compared to vehicle pretreatment (p<0.05).