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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: Arch Biochem Biophys. 2008 Dec 10;484(2):205–213. doi: 10.1016/j.abb.2008.11.027

Figure 2. Exposure to DETA NONOate does not cause barrier dysfunction in 16HBE14o- cells.

Figure 2

Effects of the indicated concentrations of DETA NONOate (100 and 500 μM) on (A) transepithelial electrical resistance and (B) FITC-dextran leakage were monitored in 16HBE14o- cells over 24 hrs. For comparison, loss of TER and increased FITC-dextran permeability upon TJ disruption by the Ca2+-chelator EGTA (2 mM) are shown (n=4). □ = control; ▴= DETA–NO 100 μM; ▾ = DETA – NO 500 μM; ⋄ = EGTA 2mM.