A and B, Morphometric analysis revealed a reduced number of TM+ and SMA+ vessels in the infarcted area of VEGF-B−/− mice, as compared to WT animals (*P<0.05) or to VEGF-B−/− mice, treated with rhVEGF-B167 (#P<0.05 vs no treatment). C–F, Immunostaining showed increased TM+ and SMA+ vessels after delivery of rhVEGF-B167 to WT mice. G and H, Systemic injection of Ad.hVEGF-B167 stimulates the growth of TM+ and SMA+ vessels in the infarct area and border zone of WT mice (*P<0.05). Scale bars: 50 μm.