Adoptive transfer of T cells from mice immunized with human papillomavirus (HPV)-16 E7 plus Fve retarded tumour growth and prolonged survival. Eight million T cells purified from mice immunized with phosphate-buffered saline (PBS) (♦), HPV-16 E7 (▪), Fve (×) or HPV-16 E7 plus Fve (▴) were adoptively transferred to recipient mice at days −1, 3, 6 and 9. Recipient mice (n= 10 per group) were inoculated subcutaneously with 5 × 104 TC-1 cells at day 0 (a). Ten days after the tumour challenge, the size of the tumour formed was measured on alternate days. Data are presented as mean ± standard error of the mean (b).