Table 3.

Ovary transplants between mutant and wild-type mice

	Number	Host	Ovaries		Litters/animal	Pups/litter
A.	2	−/−	+/−	+/−	1	1–2
	1	−/−	+/−	+/−	2	2–3
	3	−/−	−/−	+/−	1	2
						(+/−) (+/+)
B.	2	+/+	−/−	+/+	3	7  37
	3	+/+	−/−	+/+	1	4  10

(A) One or two ovaries from 4- to 6-week-old C/EBPβ-deficient mice were replaced by ovaries from heterozygous littermates. The mice were mated 14 days postsurgery, and the first litters were born 20–30 days later. The animals were sacrificed at 3–4 months of age for histological analysis (see Fig. 4). (B) One ovary each from 4- to 6-week-old wild-type 129/SV × C57BL/6 females was replaced with one ovary from age-matched C/EBPβ-deficient mice. The mice were mated 14 days postsurgery to wild-type males, and the first litters were born 20–30 days later. The genotype of the pups was determined by tail DNA analysis. The mothers were sacrificed after one or three litters for histological analysis (see Fig. 4).