Table 4.
Histological findings in 10-week-old MRLlpr/lpr mice
| MRL WT mice |
MRLlpr/lpr mice |
|||||
|---|---|---|---|---|---|---|
| Saline | P3C | LPS | Saline | P3C | LPS | |
| Histological scores | ||||||
| Activity index | ND | ND | ND | 0·6 ± 0·5 | 0·7 ± 0·4 | 3·2 ± 0·62 |
| Chronicity index | ND | ND | ND | 0·0 ± 0·0 | 0·0 ± 0·0 | 0·0 ± 0·0 |
| Glomeruli IgG deposit score | ||||||
| IgG | ND | ND | ND | 1·3 ± 0·11 | 1·2 ± 0·11 | 1·2 ± 0·11 |
| C3c | ND | ND | ND | 0·4 ± 0·31 | 0·4 ± 0·31 | 0·4 ± 0·21 |
Values are mean ± standard error of the mean; 1P < 0·05 versus wild type (WT); 2P < 0·05 versus saline; IgG, immunoglobulin G; ND, not detectable; LPS, lipopolysaccharide; P3C, pam3cys.