Figure 2.
Impaired clearance of Enterococcus faecium peritonitis during turpentine-induced acute-phase response. Mean (± SEM) E. faecium colony-forming units (CFU) in (a) peritoneal lavage fluid (PLF), (b) blood, (c) liver and (d) lungs 2 and 6 hr and 1, 2, 3 and 7 days after inoculation with 108 CFU E. faecium (at T = 0). Mice were inoculated 24 hr after subcutaneous turpentine (circles) or saline (triangles) injection; n = 8 per group at each time-point. P-values in figure represent the overall difference between groups; asterisks indicate differences between groups at one time point. *P< 0·05, **P< 0·01, ***P< 0·001 compared to saline-injected mice.