Figure 3.

Reduced circulating neutrophil numbers and peritoneal neutrophil influx in mice with a turpentine-induced acute-phase response. Mean (± SEM) of (a) circulating and (b) peritoneal neutrophils. Mice were inoculated intraperitoneally with Enterococcus faecium at T = 0, 24 hr after injection of turpentine (circles) or saline (triangles). Peritoneal levels of neutrophil attracting chemokines (c) cytokine-induced neutrophil chemoattractant (KC) and (d) macrophage inflammatory protein-2 (MIP-2) were measured 2 and 6 hr post-infection; n = 6 per group for uninfected control mice (T = 0) and n = 8 mice per group for infected mice at each time-point. P-values in figure represent the overall difference between groups; asterisks indicate differences between groups at one time-point. *P< 0·05, ***P< 0·001.