Skip to main content
. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: J Immunol. 2009 Sep 14;183(7):4715–4722. doi: 10.4049/jimmunol.0802592

Figure 6. Absence of 12/15-LO improves acid-induced acute lung injury.

Figure 6

Two hours after initiation of acid-induced ALI, gas exchange was measured in Alox15−/− and wild-type mice before and after HCl instillation (A). Permeability measured by BAL protein contents (B) compared to control mice (n ≥ 3 mice). #P < 0.05. (C) Alox15−/− mice showed significantly prolonged survival after induction of acid-induced ALI compared to HCl-treated WT mice (n = 6 per group). P < 0.001 by log rank test.