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. Author manuscript; available in PMC: 2009 Sep 29.
Published in final edited form as: J Med Chem. 2008 Jul 4;51(15):4563–4570. doi: 10.1021/jm800194k

Figure 3. Effect of compound 3b on PMET activity in acute leukemic cell lines.

Figure 3

Cells (105cells per well in 0.1 ml) were pretreated for 30 min. with 3b compound dissolved in DMSO prior to adding WST-1/mPMS (final concentration of 500 µM and 20 µM, respectively). WST-1 reduction measured in real time at 450 nm in a BMG Fluostar microplate reader. Results are averages ± S.E.M. of four independent experiments.