. Author manuscript; available in PMC: 2009 Sep 29.

Published in final edited form as: J Med Chem. 2008 Jul 4;51(15):4563–4570. doi: 10.1021/jm800194k

Table 1.

Compounds 3, 7–9.

Comp.	Formula	M.W.	Method	M.p. or ref.	Starting material ref.
3a	C₂₃H₁₅N₃O₂	365.39	1	[^a]
3b	C₂₃H₁₃Cl₂N₃O₂	434.28	1	[^b]
3c	C₂₃H₁₃Cl₂N₃O₂	434.28	1	[^b]
3d	C₂₅H₁₉N₃O₄	425.44	1	[^a]
3e	C₂₃H₁₅N₃O₄	397.39	1	335–340	[^c]
3f	C₃₁H₂₃N₃O₈	565.53	2	210–215 dec.	[^d]
3g	C₂₇H₂₅N₅O₂	451.52	1	340–350	[^e]
3h	C₂₃H₁₃F₂N₃O₂	401.37	1	347–350 dec.	[^f]
3i	C₂₅H₁₅N₃O₆	453.41	2	>360	[^g]
3j	C₂₃H₁₃Br₂N₃O₂	523.18	2	355 dec.	[^h]
3k	C₂₃H₁₅N₃O₈S₂	525.52	2	325–330
3l	C₂₃H₁₃Cl₂N₃O₂	434.28	1	332 dec.
3m	C₂₅H₁₉N₃O₄	425.44	1	>360	[ⁱ]
3n	C₂₇H₂₃N₃O₄	453.49	1	314–315 dec.	[^j]
3o	C₂₅H₁₉N₃O₂	393.44	1	[^a]
3p	C₂₇H₂₃N₃O₄	453.49	1	218–220	[^k]
3q	C₂₅H₁₉N₃O₄	425.44	1	260–262 dec.	[^k]
7a	C₂₀H₁₂N₄O₄	372.34	-	>360
7b	C₂₂H₁₆N₄O₆	432.39	-	>360
8a	C₂₆H₂₀N₄O₄	452.46	-	302–305 dec.
8b	C₂₈H₂₄N₄O₆	512.52	-	344–346 dec.
9a	C₂₂H₁₆N₄O₂	368.39	-	355–358 dec.
9b	C₂₄H₂₀N₄O₄	428.44	-	>360

^c–h

ⁱ

Ref.⁹

^j,k