Table 1.
Whole group n=144 Mean (StD) | NC§ n=26 Mean (StD) | MCI n=12 Mean (StD) | AD n=26 Mean (StD) | FTD n=24 Mean (StD) | SD n=27 Mean (StD) | PNFA n=7 Mean (StD) | PSP/CBD/DLB n=22 Mean (StD) | |
---|---|---|---|---|---|---|---|---|
Age | 63.4 (10.2) | 58.8 (12.8)* | 75.4 (9.7)† | 62.3 (8.6) | 58.9 (6.1)* | 63.5 (7.4) | 60.7 (12.1) | 69.3 (7.6)† |
Education (yrs) | 16.1 (2.7) | 16.6 (2.3) | 16.5 (2.6) | 16.0 (2.6) | 15.8 (2.2) | 16.6 (3.1) | 14.3 (2.4) | 15.8 (2.7) |
M/F | 79/65 | 10/16 | 6/6 | 14/12 | 21/3 | 13/14 | 1/6 | 14/8 |
CDR (sum of boxes) | 3.3 (2.9) | 0.8 (1.8) | 0.6 (0.6)* | 3.8 (2.4) | 5.8 (2.7)† | 3.7 (2.6) | 2.6 (2.4) | 4.4 (2.5) |
MMSE | 24.9 (5.3) | 29.4 (1.0) | 29.3 (1.0)† | 21.5 (5.5)* | 25.8 (3.0) | 23.3 (5.7) | 24.4 (3.7) | 22.4 (6.4)* |
Rey figure copy | 14.1 (3.6) | 15.8 (1.4) | 14.8 (1.4) | 12.5 (5.5) | 14.8 (2.1) | 15.4 (1.5) | 14.7 (1.6) | 11.0 (4.5)* |
Rey figure recall (30 min) | 8.1 (4.9) | 13.3 (1.5) | 8.8 (4.4) | 5.5 (5.1)* | 7.4 (4.5) | 7.2 (4.8) | 7.3 (5.3) | 7.1 (4.0) |
Digits backwards | 4.0 (1.4) | 4.7 (0.9) | 4.6 (0.8) | 3.1 (1.1)* | 4.5 (1.4) | 4.7 (1.1) | 3.1 (0.9) | 2.8 (1.5)* |
BNT | 11.1 (4.5) | 14.6 (0.8) | 13.3 (2.5) | 11.6 (3.3) | 12.3 (3.2) | 4.1 (3.7)* | 10.7 (2.9) | 12.8 (2.5) |
PPTW | 46.8 (6.7) | 51.4 (1.0) | 51.3 (0.8)* | 48.2 (3.9) | 47.3 (6.1) | 37.8 (8.1)* | 49.1 (2.5) | 47.1 (4.1) |
PPTP | 45.9 (6.9) | 50.6 (1.7) | 50.8 (1.2)† | 46.4 (6.7) | 46.1 (6.8) | 38.1 (7.4)* | 47.3 (4.3) | 45.7 (5.0) |
significantly different on all neuropsychological measures from other diagnostic groups combined (p<0.05)
significantly lower than other diagnostic groups combined (p<0.05)
significantly higher than other diagnostic groups combined (p<0.05)
NC = normal control subjects; MCI = mild cognitive impairment; AD = Alzheimer’s Disease; FTD = fronto-temporal dementia; SD = semantic dementia; PNFA = progressive non-fluent aphasia; PSP = progressive supranuclear palsy; CBD = corticobasal degeneration; DLB = diffuse Lewy body dementia