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Effect of MMP9 deficiency on embryonic kidney maturation. Representative photographs of E11.5 (A and B) and E12.5 (C and D) kidneys from MMP9+/+ (A and C) and MMP9−/− mice (B and D) stained with calbindin D-28K to delineate ureteric bud (arrow). Please note the defect in ureteric bud elongation and branching in MMP9−/− embryonic kidney. Bar: 250 μm.
