Table 4.
Adjusted incidence rate ratio (95% confidence interval) of all-cause and cardiovascular mortality, by category of eGFR: NHANES IIIa
| Parameter | eGFR Based on Creatinine, Age, Race, and Gender (ml/min per 1.73 m2) |
|||||
|---|---|---|---|---|---|---|
| ≥120 | 90 to 119 | 60 to 89 | 30 to 59 | 15 to 29 | Overall | |
| All-cause mortality: eGFR based on cystatin C, age, race, and gender (ml/min per 1.73 m2) | ||||||
| ≥120 | 0.48 (0.15 to 1.54) | 1.38 (0.76 to 2.50) | 0.36 (0.05 to 2.62) | b | b | 0.93 (0.56 to 1.56) |
| 90 to 119 | 1.32 (0.83 to 2.11) | 1.00 (Ref) | 0.76 (0.51 to 1.13) | b | b | 1.00 (Ref) |
| 60 to 89 | 1.89 (1.19 to 3.00) | 1.05 (0.78 to 1.41) | 0.94 (0.72 to 1.22) | 1.01 (0.68 to 1.50) | b | 1.03 (0.84 to 1.26) |
| 30 to 59 | b | 1.73 (1.14 to 2.61) | 1.46 (1.10 to 1.94) | 1.76 (1.32 to 2.35) | b | 1.68 (1.35 to 2.09) |
| <30 | b | b | 2.38 (1.01 to 53.61) | 3.33 (2.30 to 4.81) | 2.90 (1.81 to 4.63) | 3.25 (2.42 to 4.37) |
| Overall | 1.36 (1.02 to 1.83) | 1.00 (Ref) | 0.94 (0.81 to 1.09) | 1.42 (1.20 to 1.68) | 2.39 (1.64 to 3.48) | |
| Cardiovascular mortality: eGFR based on cystatin C, age, race, and gender (ml/min per 1.73 m2) | ||||||
| ≥120 | c | 1.61 (0.55 to 4.70) | c | b | b | 0.97 (0.34 to 2.73) |
| 90 to 119 | 0.60 (0.18 to 2.02) | 1.00 (Ref) | 0.75 (0.37 to 1.52) | b | b | 1.00 (Ref) |
| 60 to 89 | 1.87 (0.82 to 4.26) | 1.17 (0.70 to 1.97) | 1.12 (0.70 to 1.79) | 0.92 (0.46 to 1.84) | b | 1.29 (0.90 to 1.86) |
| 30 to 59 | b | 2.13 (1.09 to 4.14) | 1.83 (1.12 to 3.00) | 2.40 (1.47 to 3.93) | b | 2.39 (1.63 to 3.50) |
| <30 | b | b | b | 3.61 (1.96 to 6.63) | 3.74 (1.82 to 7.67) | 4.15 (2.56 to 6.71) |
| Overall | 0.84 (0.45 to 1.57) | 1.00 (Ref) | 1.03 (0.82 to 1.30) | 1.61 (1.25 to 2.08) | 2.50 (1.44 to 4.34) | |
aAdjusted for age, gender, race/ethnicity, previous CVD, BP category, use of antihypertensive medication, diabetes status, smoking status, body mass index, LDL and HDL cholesterol, log triglycerides, and CRP category.
bn < 30.
cNo deaths.