Table 1.
Demographic and Illness History Variables (N=58)
| Variablea | Value |
|---|---|
| Mean (SD) | |
| Age, y | 14.5 (1.6) |
| K-SADS depression scale ratingb | 28.6 (9.4) |
| K-SADS mania scale ratingb | 24.3 (9.5) |
| CGAS rating26 | |
| Current (last 2 wk) | 57.8 (11.1) |
| Most severe past episode | 44.9 (12.9) |
| Highest in prior year | 59.7 (11.1) |
| No. (%) | |
| Sex | |
| Female | 33 (56.9) |
| Race | |
| African American | 1 (1.7) |
| Native American | 1 (1.7) |
| Asian/Pacific Islander | 1 (1.7) |
| Biracial | 3 (5.2) |
| Hispanic ethnicity | 3 (5.2) |
| Live with both biological parents | 26 (44.8) |
| Bipolar I | 38 (65.5) |
| Bipolar II | 6 (10.3) |
| Bipolar not otherwise specified | 14 (24.1) |
| Index mood episode | |
| Depression | 18 (31.0) |
| Mania | 12 (20.7) |
| Mixed | 3 (5.2) |
| Subthresholdc | 25 (43.1) |
| Comorbid disorders | |
| Anxiety | 2 (3.5) |
| ADHD | 11 (19.0) |
| ODD | 7 (12.1) |
| Substance abuse or dependence | 0 (0.0) |
| Medication treatments at study entry | |
| 1 mood stabilizer | 35 (60.0) |
| 2 mood stabilizers | 9 (15.5) |
| 1 atypical antipsychotic | 34 (58.6) |
| 2 atypical antipsychotics | 7 (12.1) |
| Adjunctive antidepressant | 13 (22.4) |
| Adjunctive anxiolytic | 3 (5.2) |
| Type of mood stabilizer at study entry | |
| Divalproex sodium | 7 (12.1) |
| Lithium | 21 (36.2) |
| Lamotrigine | 3 (5.2) |
| Carbamazepine | 1 (1.7) |
| Oxcarbazepine | 13 (22.4) |
| Topiramate | 3 (5.17) |
| Type of antipsychotic at baseline | |
| Aripiprazole | 10 (17.2) |
| Risperidone | 8 (13.8) |
| Quetiapine | 21 (36.2) |
| Olanzapine | 4 (6.9) |
Abbreviations: ADHD, attention deficit hyperactivity disorder; CGAS, Children's Global Assessment Scale; K-SADS, Kiddie Schedule for Affective Disorders and Schizophrenia; ODD, oppositional defiant disorder.
a
None of these variables significantly distinguished between the psychosocial treatment groups or sites, based on Mantel-Haenszel χ2 and 2-way analysis of variance tests.
b
Refers to scores collected at entry into the study, covering the worst 1- to 2-week period in the previous 3 months.
c
Adolescents with subthreshold index mood episodes had at least 1 to 2 weeks in the past 3 months with Adolescent Longitudinal Interval Follow-up Evaluation mania or depression scores ≥3 and <5.