Figure 7.

Pten deletion enhances post-stroke neuroblast migration. a, DCX labeling in peri-infarct cortex and SEZ. DCX⁺ cells in control and mutant 7 d after stroke. Right panel shows stereological quantification of DCX⁺ cells in peri-infarct cortex. Scale bars: top, 100 μm; bottom, 25 μm. n = 6. b, Representative images of P-S6 staining from both hemispheres of mutant mouse. Left panel shows hemisphere containing peri-infarct cortex which has increased staining for p-S6 in peri-infarct cortex when compared with uninjured cortex in the same animal (right panel). DAPI is used as counterstain to visualize nuclei. Scale bar, 50 μm. CTX, Cortex; CC, corpus callosum.