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. Author manuscript; available in PMC: 2009 Sep 29.
Published in final edited form as: J Biomol Screen. 2008 Sep 23;13(9):870–878. doi: 10.1177/1087057108323909

Figure 6. Confirmation of selected compounds exhibiting ≥ 60% inhibition in the primary screen.

Figure 6

Compounds were plated at 3 concentrations to confirm activity and determine dose-dependence of calpain inhibition (filled symbols) and the assay was performed as described for the screen. Cytotoxicity experiments were conducted in tandem (open symbols). Error bars represent the standard deviation in percent inhibition among 4 replicates for each concentration.