Table 1.

Characteristics of Patients on Systemic α-1 Adrenergic Receptor Antagonists and Controls^*

Variable	Study Group (n=29, 45 eyes)	Control Group (n=22, 31 eyes)	P value§
Age (years)	70.6 ±7.6	67.1 ±9.1	0.061†
Race (C/AD/H)	25/1/3	19/1/2	0.541‡
Eye color (light/dark)	10/19	7/15	0.741
Photopic pupillary diameter (mm)	2.06 ±0.5 (1 – 3.4)	2.50 ±0.6 (1.7 – 3.9)	0.001
Iris thickness measurements
Dilator muscle region (μm)	354.6 ±83.7 (176.7 – 522)	446.9 ±92.6 (291.3 – 611)	<0.001
Sphincter muscle region (μm)	473.2 ±76.5 (359.3 – 681.3)	460.5 ±99.5 (328.3 – 745)	0.530
DMR/SMR ratio	0.75 ±0.2 (0.36 – 1.07)	0.98 ±0.1 (0.79 – 1.23)	<0.001

C = Caucasian; AD = African descendent; H = Hispanic; DMR = dilator muscle region; SMR = sphincter muscle region.

^*Data are given as mean ± standard deviation (range) whenever indicated.

^†Independent sample t-test.

^‡Chi-square test.

^§GLM (General linear model).