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. Author manuscript; available in PMC: 2009 Sep 29.
Published in final edited form as: Clin Chem. 2009 Feb 20;55(4):748–756. doi: 10.1373/clinchem.2008.113381

Fig. 4. Comparison of regular PCR/TaqMan genotyping with COLD-PCR/TaqMan genotyping for the G>A mutation in codon 273 of TP53 exon 8.

Fig. 4

Serial dilutions into wild-type DNA of SW480 cell line DNA containing the G_A mutation in codon 273 of TP53 exon 8 were evaluated for the codon 273 mutation with regular PCR/TaqMan genotyping (A) and COLD-PCR/TaqMan genotyping (B). Clinical tumor samples from 3 NSCLC cancer patients (TL6, TL8, and TL18) and a colon cancer sample (CT20) were evaluated for the codon 273 mutation with regular PCR/TaqMan genotyping (C) and COLD-PCR/TaqMan genotyping (D).