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. 2009 Sep 29;73(13):1058–1065. doi: 10.1212/WNL.0b013e3181b9c8b9

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Figure 1 Gray matter loss in subjects with IVS10+16, IVS10+3, N279K, S305N, P301L, and V337M mutations

Results are shown on 3-dimensional renderings of the brain and show regions of gray matter loss in each group compared with controls. CDR-SB = median Clinical Dementia Rating Scale sum of boxes; DD = median disease duration (time from onset to scan).