Fig. 5. Plasma vRNA levels in SHIV-immunized monkeys, SHIV-immunized, CD8+ lymphocyte-depleted monkeys and naive control monkeys after vaginal challenge with SIVmac239.
Comparison of plasma SIVgag concentration (copies/ml) at (a) 7 days and (b) 14 days p.c.; and plasma SIVenv concentration (copies/ml) at (c) 7 days and (d) 14 days p.c. in naïve control and CD8+ T cell-depleted SHIV-immunized animals. Comparison of plasma HIVenv concentration (copies/ml) in SHIV-immunized and CD8+ T cell-depleted, SHIV-immunized animals at (e) 7 days and (f) 14 days p.c.. Each symbol represents the result for an individual animal. The horizontal line indicates the mean plasma vRNA level in each animal group. P values were generated with an unpaired one-tailed T test.