Table 1.

Principal Component Analysis: Pattern Matrix-Rotated Loadings^*

	Five Cardiovascular Health Study Frailty Criteria Components†		Ten Expanded MacArthur Study of Successful Aging Frailty Criteria Components‡
Criterion	1	2	1	2	3	4
Slower gait	0.71				0.75
Weaker grip	0.61			0.37	0.50
Lower physical activity	0.60				0.44	− 0.33
Weight loss	0.27	0.77				0.69
Exhaustion	0.31	− 0.63		0.81
Lower cognitive function				− 0.36	0.56
Subjective weakness				0.73
Anorexia						0.71
Higher IL-6			0.85
Higher CRP			0.85
Initial eigenvalue	1.4	1.0	1.8	1.5	1.2	1.1
Percentage of variance explained	28	20	18	15	12	11

^*Loadings <0.20 are omitted from the table.

^†The rotated factor-loading matrix of the five Cardiovascular Health Study frailty criteria indicates a two-component structure in which slower gait, weaker grip, and lower physical activity define one component (subdimension), and exhaustion and weight gain (not loss) defined the second component (subdimension).

^‡The rotated factor-loading matrix of the expanded frailty criteria indicates a four-component structure in which higher interleukin (IL)-6 and C-reactive protein (CRP) define the first of these components (subdimensions), exhaustion and subjective weakness the second, slower gait, weaker grip, lower physical activity and lower cognitive function the third, and weight loss and anorexia the fourth.