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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Birth Defects Res C Embryo Today. 2009 Jun;87(2):143–164. doi: 10.1002/bdrc.20153

Figure 3.

Figure 3

(A). Nonlinear scaling of total number of signaling proteins in eukaryotes with proteome size along with the best-fit curve. One hundred seventy signaling domains were studied in 43 completely sequenced eukaryotic genomes. (B). Scaling of serine/threonine/tyrosine (S/T/Y) kinases in eukaryotes with proteome size with the best-fit curve. (C). Scaling of eukaryotic transcription factors with proteome size with the best-fit curve. Note that multicellular forms have higher numbers of specific transcription factors. (D). Scaling of prokaryotic specific transcription factors with the HTH domain from complete genomes with the best-fit curve.