Table 2.
Statistical analysis of the binding intensity of native and recombinant frutalin in human prostate tissues
| Frutalin/source | Histological diagnosis | Number of cases for each binding intensity* | Mann-Whitney U analysis | ||||
| 0 | + | ++ | +++ | Mean Rank | P | ||
| Native (A. incisa) |
Benign prostate hyperplasia | 0 (0%) |
4 (16%) |
13 (52%) |
8 (32%) |
19.90 | 0.051I |
| Prostate carcinoma | 0 (0%) |
1 (5%) |
7 (35%) |
12 (60%) |
26.88 | ||
| Recombinant (P. pastoris) |
Benign prostate hyperplasia | 25 (100%) |
0 (0%) |
0 (0%) |
0 (0%) |
16.00 | 0.000S |
| Prostate carcinoma | 6 (30%) |
9 (45%) |
4 (20%) |
1 (5%) |
31.75 | ||
*The binding intensity was converted numerically as: negative (0) = 0, low (+) = 1, moderate (++) = 2 and strong (+++) = 3; I Insignificant statistical result; S Significant statistical result.