Table 1.
Baseline characteristics of patients with hypertension, microalbuminuria, and type 2 diabetes followed from baseline to 12 weeks. Figures are means (SD) unless stated otherwise
| Candesartan | Lisinopril | |
|---|---|---|
| No of patients | 99 | 98 |
| Age (years) | 59.7 (9.9) | 60.0 (8.5) |
| No of men | 66/33 | 62/36 |
| Body mass index (kg/m2) | 30.7 (4.3) | 29.8 (3.8) |
| Duration of hypertension (years) | 8.3 (8.8) | 9.0 (8.9) |
| Duration of diabetes (years) | 9.8 (7.5) | 8.4 (7.3) |
| Systolic blood pressure (mm Hg) | 162.7 (17.7) | 162.6 (17.6) |
| Diastolic blood pressure (mm Hg) | 96.0 (6.2) | 95.7 (6.2) |
| Urinary albumin:creatinine ratio (mg/mmol)* | 5.9 (1.1) | 6.6 (1.1) |
| Serum creatinine (μmol/l) | 85.8 (18.9) | 85.0 (16.8) |
| Creatinine clearance (ml/min) | 103.1 (37.7) | 96.0 (28.7) |
| Haemoglobin A1C (%) | 7.6 (1.2) | 7.6 (1.6) |
| ACE genotype (DD/ID/II/not known) | 28/45/14/12 | 32/41/20/5 |
*
Geometric mean (tolerance factors).