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. 2000 Dec 9;321(7274):1440–1444. doi: 10.1136/bmj.321.7274.1440

Table 2.

Adjusted* mean reductions in blood pressure and urinary albumin:creatinine ratio from baseline to 12 weeks in patients with hypertension, microalbuminuria, and type 2 diabetes

Candesartan Lisinopril Adjusted mean difference between treatments
Sitting diastolic blood pressure (mm Hg)  9.5 (7.7 to 11.2); P<0.001 9.7 (7.9 to 11.5); P<0.001 0.2 (−2.3 to 2.7); P >0.20
Sitting systolic blood pressure (mm Hg) 12.4 (9.1 to 15.8); P<0.001 15.7 (12.2 to 19.2); P<0.001 3.3 (−1.5 to 8.2); P=0.18
Urinary albumin:creatinine ratio (%) 30 (15 to 42); P<0.001 46 (35 to 56); P<0.001 30 (1 to 71); P=0.058
*

Adjusted for centre, treatment, baseline value, weight, and change in diastolic blood pressure. 

Relative reduction.