Table 4.

Adjusted^* mean reduction in blood pressure and urinary albumin:creatinine ratio from baseline to 24 weeks in patients with hypertension, microalbuminuria, and type 2 diabetes

	Candestartan	Lisinopril	Combination	Adjusted mean difference
				Combination v candestartan	Combination v lisinopril
Sitting diastolic blood pressure (mm Hg)	10.4 (7.7 to 13.1); P<0.001	10.7 (8.0 to 13.5); P<0.001	16.3 (13.6 to 18.9); P<0.001	5.9 (2.1 to 9.7); P=0.003	5.6 (1.7 to 9.4); P=0.005
Sitting systolic blood pressure (mm Hg)	14.1 (8.9 to 19.2); P<0.001	16.7 (11.4 to 21.9); P<0.001	25.3 (20.3 to 30.3); P<0.001	11.2 (4.1 to 18.4); P=0.002	8.6 (1.4 to 15.9); P=0.02
Urinary albumin:creatinine ratio (%)	24 (0 to 43); P=0.05	39 (20 to 54); P<0.001	50 (36 to 61); P<0.001	34 (3 to 55); P=0.04	18 (−20 to 44); P>0.20

^*Adjusted for centre, treatment, baseline value, weight, and change in diastolic blood pressure.