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. Author manuscript; available in PMC: 2009 Sep 30.
Published in final edited form as: FASEB J. 2008 Feb 19;22(6):1886–1893. doi: 10.1096/fj.07-100925

Figure 3.

Figure 3

Xp-HB-IGF-1 and Xp-IGF-1 activity is equivalent to IGF-1. A) Dose-response for phosphorylation of the IGF-1 receptor and Akt: neonatal rat cardiac myocytes were incubated with control IGF-1, Xp-HB-IGF-1, or Xp-IGF-1 at the indicated doses for 20 min. B) Time course of Akt phosphorylation: neonatal rat cardiac myocytes were incubated with 30 nM of control IGF-1, Xp-HB-IGF-1 or Xp-IGF-1 for the indicated time periods. The results shown are representative of results from 3 independent experiments. P-IGF-R and P-Akt represent phosphorylation of IGF-1 receptor and phosphorylation of Akt, respectively.