TABLE I.
Effect of novel home cage exposure on turnover of NE, DA, and 5HT in the vicinity of the LC
Group | DA | DOPAC | DOPAC/DA | NE | MHPG | MHPG/NE | 5HT | 5HIAA | 5HIAA/5HT |
---|---|---|---|---|---|---|---|---|---|
Control (9) | 0.019 | 0.015 | 0.786 | 0.349 | 0.016 | 0.047 | 0.398 | 0.485 | 1.109 |
0.002 | 0.002 | 0.027 | 0.040 | 0.002 | 0.001 | 0.042 | 0.112 | 0.147 | |
Novel cage (9) | 0.023 | 0.025 | 1.049 | 0.369 | 0.023 | 0.060 | 0.406 | 0.568 | 1.281 |
0.001 | 0.003 | 0.072 | 0.032 | 0.003 | 0.003 | 0.038 | 0.134 | 0.189 | |
t | −1.76 | −3.35 | 3.43 | −0.40 | 1.92 | 4.40 | −0.13 | −0.47 | −0.72 |
p | 0.0960 | 0.0004 | 0.0034 | NS | 0.0720 | 0.0004 | NS | NS | NS |
Values are means and SEMs of groups of 9 mice. Values of amines are in ng/mg wet weight.