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. 2009 Oct 9;4(10):e7403. doi: 10.1371/journal.pone.0007403

Figure 1. Structures of TFE and TOY constructs.

Figure 1

(A) Schematic diagrams of the constructs showing the relative sizes of the human TLR4 ectodomain (TLR4), VLRB.61 fragment (VLR) of hagfish, and human IgG-Fc (Fc). Numbers indicate amino acids of the parental proteins. (B) Crystal structures based on computer modeling. The domains depicted are TLR4 (red), VLR (yellow), and Fc (blue). (C) Each 2 µg of reduced (R) and nonreduced (NR) proteins was separated by SDS-PAGE and stained with Coomassie blue. Molecular masses (kDa) are indicated at left.