TABLE 3. Relative risks (RR) of endometrial cancer according to different measures of physical activity at baseline.
No. of women | No. of cases | Age-adjusted RR (95% confidence interval) | Multivariable-adjusted RRa (95% confidence interval) | |
---|---|---|---|---|
Total energy expenditure, MET-hours/week: | ||||
<2.7 | 8124 | 80 | 1.42 (1.01–1.98) | 1.15 (0.79–1.67) |
2.7–8.4 | 8128 | 66 | 1.14 (0.81–1.62) | 0.99 (0.68–1.44) |
8.4–20.4 | 8221 | 58 | 1.97 (0.68–1.40) | 0.93 (0.64–1.35) |
≥20.4 | 8169 | 60 | 1.00 (referent) | 1.00 (referent) |
p,trend = 0.02 | p.trend = 0.39 | |||
Time spent walking per week: | ||||
No regular walking | 6727 | 55 | 1.07 (0.76–1.50) | 0.88 (0.61–1.27) |
1–59 minutes | 8682 | 65 | 0.99 (0.71–1.37) | 0.90 (0.64–1.27) |
1.0–1.5 hours | 6960 | 61 | 1.13 (0.81–1.57) | 1.07 (0.76–1.51) |
≥ 2 hours | 10273 | 83 | 1.00 (referent) | 1.00 (referent) |
p.trend = 0.87 | p.trend = 0.37 | |||
Usual walking pace, km/hr: | ||||
No regular walking | 5825 | 48 | 1.12 (0.78–1.61) | 0.82 (0.55–1.22) |
<3.2 | 3815 | 44 | 1.55 (1.07–2.24) | 1.08 (0.72–1.62) |
3.2–4.7 | 12459 | 94 | 1.00 (0.74–1.35) | 0.85 (0.62–1.16) |
≥ 4.8 | 10543 | 78 | 1.00 (referent) | 1.00 (referent) |
p.trend = 0.19 | p.trend = 0.54 | |||
Vigorous energy expenditure, MET-hours/week: | ||||
None (0) | 18875 | 177 | 1.00 (0.69–1.47) | 0.87 (0.58–1.31) |
1–3.3 | 3455 | 26 | 0.84 (0.50–1.42) | 0.71 (0.41–1.23) |
3.3–7.5 | 3448 | 14 | 0.46 (0.24–0.86) | 0.38 (0.20–0.76) |
7.5–15.0 | 3531 | 16 | 0.49 (0.27–0.90) | 0.51 (0.27–0.93) |
<15.0 | 3333 | 31 | 1.00 (referent) | 1.00 (referent) |
p.trend = 0.04 | p.trend = 0.23 |
Adjusted for age, BMI, smoking status, alcohol use, saturated fat intake, fiber intake, fruit/vegetable intake, parity, use and type of hormone therapy, and menopausal status.