Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2010 Oct 1.

Published in final edited form as: Dev Biol. 2009 Jul 23;334(1):97–108. doi: 10.1016/j.ydbio.2009.07.021

In situ hybridization for Bmp4 and Fgf10 mRNA in E15 control (A to C) and CatnbEx3(cko/+) (D to F) lungs and trachea. Bmp4 was nearly undetectable in control trachea (B). Arrows in panel E indicate induction of high Bmp4 levels in polyp epithelial cells in mutant trachea. Scale bar: 40 um (A, D); 80 um (B, C, E, F).

Panel G. Relative mRNA levels of Bmp4 in mutant (M) vs. control lungs (C) by quantitative RT-PCR. Levels of mRNA were normalized to that of TATA Binding Protein (TBP). * indicates P<0.05.

In situ hybridization for Bmp4 and Fgf10 mRNA in E15 control (A to C) and CatnbEx3(cko/+) (D to F) lungs and trachea. Bmp4 was nearly undetectable in control trachea (B). Arrows in panel E indicate induction of high Bmp4 levels in polyp epithelial cells in mutant trachea. Scale bar: 40 um (A, D); 80 um (B, C, E, F).

Panel G. Relative mRNA levels of Bmp4 in mutant (M) vs. control lungs (C) by quantitative RT-PCR. Levels of mRNA were normalized to that of TATA Binding Protein (TBP). * indicates P<0.05.