Table 2. Serum Neutralization of CTR203.
TIER 1 | TIER 2 | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
STRAIN | SF162.LS | BAL.26 | SS196.1 | 6535.3 | QH0692.4 2 |
SC422661 .8 |
PVO.4 | TRO.11 | AC10.0.2 9 |
RHPA425 9.7 |
THRO415 6.18 |
REJO454 1.67 |
TRJO455 1.58 |
WITO416 0.33 |
CAAN53 42.A2 |
SIVmac25 1.WY5 |
ID50 | 9250 | 756 | 278 | 121 | 36 | 421 | 80 | 77 | <20 | 891 | 129 | 162 | 44 | 228 | 264 | <20 |
ID 50 values are the reciprocal dilutions required to achieve 50% inhibition of infectivity in a Tzm-bl assay (Li et al., 2005). The viral strains are divided into Tier 1 and Tier 2 viruses, the former being easier to neutralize (Li et al., 2005).