Table 4.

Questionnaire Test Characteristics ^*

Modality	Sensitivity† (95% CI)	Specificity† (95% CI)	Report to Records‡	Concordance† (95% CI)	Positive Predictive Value† (95% CI)	Negative Predictive Value† (95% CI)
CRC
Overall	0.94 (0.90–0.97)	0.63 (0.47–0.76)	1.04	0.88 (0.83–0.92)	0.91 (0.86–0.95)	0.74 (0.57–0.85)
Durham	0.95 (0.87–0.98)	0.60 (0.39–0.78)	1.05	0.88 (0.80–0.93)	0.90 (0.82–0.95)	0.75 (0.50–0.90)
Minneapolis	0.94 (0.86–0.98)	0.65 (0.43–0.82)	1.02	0.88 (0.80–0.93)	0.92 (0.83–0.96)	0.72 (0.49–0.88)
FOBT
Overall	0.75 (0.63–0.84)	0.84 (0.77–0.89)	1.13	0.81 (0.75–0.86)	0.66 (0.54–0.76)	0.89 (0.82–0.93)
Durham	0.78 (0.62–0.88)	0.84 (0.73–0.91)	1.06	0.82 (0.73–0.88)	0.74 (0.58–0.85)	0.87 (0.76–0.93)
Minneapolis	0.71 (0.51–0.85)	0.83 (0.73–0.90)	1.25	0.80 (0.71–0.87)	0.57 (0.39–0.73)	0.90 (0.81–0.95)
Sigmoidoscopy
Overall	0.75 (0.60–0.86)	0.91 (0.86–0.95)	1.10	0.88 (0.83–0.92)	0.68 (0.53–0.80)	0.94 (0.88–0.97)
Durham	0.80 (0.36–0.97)	0.93 (0.85–0.97)	2.20	0.92 (0.85–0.96)	0.36 (0.15–0.65)	0.99 (0.93–1.00)
Minneapolis	0.74 (0.58–0.86)	0.89 (0.79–0.95)	0.94	0.84 (0.76–0.90)	0.79 (0.62–0.90)	0.87 (0.76–0.93)
Colonoscopy
Overall	0.91 (0.84–0.96)	0.86 (0.77–0.91)	1.05	0.89 (0.83–0.92)	0.87 (0.79–0.92)	0.90 (0.82–0.95)
Durham	0.94 (0.83–0.99)	0.94 (0.83–0.98)	1.00	0.94 (0.87–0.97)	0.94 (0.83–0.99)	0.94 (0.83–0.98)
Minneapolis	0.89 (0.77–0.95)	0.77 (0.63–0.87)	1.09	0.83 (0.75–0.89)	0.81 (0.69–0.89)	0.86 (0.72–0.94)
BE
Overall	0.88 (0.51–1.00)	0.93 (0.88–0.96)	2.63	0.93 (0.88–0.95)	0.33 (0.17–0.55)	0.99 (0.97–1.00)
Durham	0.75 (0.29–0.96)	0.91 (0.83–0.95)	3.00	0.90 (0.82–0.95)	0.25 (0.09–0.54)	0.99 (0.93–1.00)
Minneapolis	1.00 (0.45–1.00)	0.95 (0.88–0.98)	2.25	0.95 (0.89–0.98)	0.44 (0.19–0.73)	1.00 (0.95–1.00)

^*calculated upper 95% confidence levels >1.00 were capped at 1.00

^†medical record documentation was the reference standard

^‡definition provided in text