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. Author manuscript; available in PMC: 2010 Aug 15.
Published in final edited form as: J Infect Dis. 2009 Aug 15;200(4):609–613. doi: 10.1086/600891

Figure 1.

Figure 1

Power of logrank test as a function of relative risk (RR). Unless indicated otherwise, simulations assumed equal numbers of animals allocated to the vaccine (nv) and control (nc) arms, total sample size N = 50, maximum of cmax = 10 challenges per animal, per-challenge probability of infection for controls p0 =0.5, and all animals susceptible to infection. The horizontal gray line corresponds to the significance level α=0.05. Power of likelihood ratio test and Fisher’s exact test is similar (results not shown).